5-Bromo-2-(trifluoromethyl)pyridine-3-carboxylic acid

5-Bromo-2-(trifluoromethyl)pyridine-3-carboxylic acid - Names and Identifiers

Name	5-bromo-2-(trifluoromethyl)pyridine-3-carboxylic acid
Synonyms	5-Bromo-2-trifluoromethyl-nicotinic acid 5-BROMO-2-(TRIFLUOROMETHYL)NICOTINIC ACID 5-Bromo-2-(trifluoromethyl)pyridine-3-carboxylic acid 5-bromo-2-(trifluoromethyl)pyridine-3-carboxylic acid 3-Pyridinecarboxylic acid,5-bromo-2-(trifluoromethyl)-
CAS	436799-36-9
InChI	InChI=1/C7H3BrF3NO2/c8-3-1-4(6(13)14)5(12-2-3)7(9,10)11/h1-2H,(H,13,14)

5-Bromo-2-(trifluoromethyl)pyridine-3-carboxylic acid - Physico-chemical Properties

Molecular Formula	C7H3BrF3NO2
Molar Mass	270
Density	1.864g/cm³
Boling Point	309.695°C at 760 mmHg
Flash Point	141.099°C
Vapor Presure	0mmHg at 25°C
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.519

5-Bromo-2-(trifluoromethyl)pyridine-3-carboxylic acid - Introduction

5-bromo-2-(trifluoromethyl)pyridine-3-carboxylic acid is an organic compound with the formula C7H3BrF3NO2.

Its properties are as follows:
Appearance: colorless solid
Melting point: 71-73 degrees Celsius
Boiling point: 242-243 degrees Celsius
Solubility: Soluble in some organic solvents, such as alcohols and ethers.

Its main uses are as follows:
1. as an intermediate of organic synthesis reaction, used in the synthesis of other organic compounds.
2. for the synthesis of pesticides, as pesticides and herbicides raw materials.

The method of preparing 5-bromo-2-(trifluoromethyl)pyridine-3-carboxylic acid can be carried out by the following steps:
1. First, trifluoromethyl nicotinic acid is added to bromoacetic acid to prepare 5-bromo-2-(trifluoromethyl)pyridine-3-carboxylic acid ethyl ester.
2. Then, the acid hydrolysis reaction is carried out under the catalysis of sulfuric acid to convert the ethyl ester into acid.

About safety information:
1. 5-bromo-2-(trifluoromethyl)pyridine-3-carboxylic acid should pay attention to fire prevention and static electricity accumulation during carrying, storage and use, and avoid contact with flammable materials.
2. in the operation, need to wear protective glasses and gloves, avoid direct contact with the skin and eyes.
3. If inhalation or touch occurs, rinse immediately with plenty of water and seek medical help.
4. This compound may be toxic to aquatic organisms and should not be discharged into water bodies.

In addition, prior to the use and handling of 5-bromo-2-(trifluoromethyl)pyridine-3-carboxylic acid, detailed toxicity and safety information should be checked and safe practices followed.

Last Update：2024-04-10 22:29:15